https://jaec.vn/index.php/JAEC/issue/feedJournal of Advanced Engineering and Computation2023-12-30T20:35:45+07:00JAECjaec@tdtu.edu.vnOpen Journal Systems<strong>Issued quarterly (4 issues per year)</strong>https://jaec.vn/index.php/JAEC/article/view/416Simulation based Comparative Review on a Metasurface based Perfect Absorber2023-12-30T20:30:38+07:00Jigar Patel209999915001@gtu.edu.inRahul Mehtardmehta@hotmail.comIn this paper, the different research papers are studied and comparatively analyzed to carry out the simulation based survey of various proposals for improvement to design Metarsurface based Perfect Absorber for GHz and THz frequency band for RF Energy Harvesting applications. Using a structure that can effectively absorb the most radiation is one of the biggest obstacles in reducing the impact of EM wave radiation. A perfect absorber may be created using variety of structures and materials with various specifications. Various structures are designed and simulated by different authors in variety of simulation softwares using useful parameters. Three distinct structures have been created, two of which were created using CST Microwave Studio and the third using HFFS for comparative study. A perfect absorber can be constructed for GHz and THz for dual band and multiband since the operating frequency range and band are not limited.2023-12-30T20:04:18+07:00Copyright (c) 2023 Journal of Advanced Engineering and Computationhttps://jaec.vn/index.php/JAEC/article/view/429Chattering-Free Second Order Robustness Sliding Mode Controller for Complex Interconnected Systems: A Moore-Penrose Inverse Technique2023-12-30T19:03:06+07:00Phuoc Nguyen Vanvanphuoc@hitu.edu.vnTrang Nguyen-Congnguyencongtrang@tdtu.edu.vn<p>In this paper, a novel second order sliding mode control approach is extended to<br />a class of complex interconnected systems with mismatched interconnections and unknown perturbations. The key contribution of this paper is to cancel two common restrictions clogging the application of the variable structure control to complex interconnected systems: 1) all of state variables must be accessible; 2) the control input is affected by chattering problems. First, a novel reduced-order sliding mode estimator (ROSME) is proposed to estimate the unmeasurable variables. Second, based on Moore-Penrose inverse technique and ROSME tool, a new decentralized chattering-free second order robustness sliding mode controller (CSORSMC) is developed to force the system states to stay in a sliding surface from the initial period instance and attenuate the chattering phenomenon in the control signal. Besides, a novel appropriate linear matrix inequality (LMI) requirement is proved such that the plant in sliding mode is asymptotically stable. Lastly, a mathematical model including two subsystems is simulated which confirms the usefulness and advantages of proposed technique.</p>2023-12-30T20:04:18+07:00Copyright (c) 2023 Journal of Advanced Engineering and Computationhttps://jaec.vn/index.php/JAEC/article/view/431Design And Evaluating The Efficacy Of Novel Antibodies Enhancing Binding On CTLA-4 And PD-1 Immune Checkpoints2023-12-30T20:32:56+07:00Nguyen Huy Hoang Voh1900063@student.tdtu.edu.vnHuong Thi Thu Phungorchard1985@gmail.comKhanh Linh Chungchungkhanhlinh@tdtu.edu.vnThien Y Vuvuthieny@tdtu.edu.vn<p>Immune checkpoint proteins, including CTLA-4 and PD-1, have emerged as promising targets for cancer immunotherapy due to their vital role in immune regulation. In this comprehensive study, we conducted a thorough analysis of antibody-protein interactions by employing structural analysis, mutational studies, and antibody-antigen docking simulations. Our findings revealed that antibodies <strong>1</strong> and <strong>2</strong> exhibited strong binding affinities towards CTLA-4 and PD-1 proteins, respectively. Further analysis through alanine scanning identified specific residues, namely Tyr91 on antibody <strong>1</strong>, along with Asn31 and Asp96 on antibody <strong>2</strong>, as potential mutation sites. Introducing these mutations resulted in the generation of two novel antibodies, <strong>1a</strong>, <strong>2a</strong> and <strong>2b</strong>, which displayed enhanced binding affinity towards their respective target proteins. With their improved binding capabilities, these novel antibodies hold tremendous promise for enhancing the effectiveness of antibody-based therapies designed to target immune checkpoints in cancer treatment. The ultimate objective is to significantly improve the health outcomes of patients by leveraging the potential of these novel antibodies.</p>2023-12-30T20:04:18+07:00Copyright (c) 2023 Journal of Advanced Engineering and Computationhttps://jaec.vn/index.php/JAEC/article/view/441Free vibration analysis of functionally graded triply periodic minimal surface plates using a first order shear deformation theory and meshfree method2023-12-30T20:35:45+07:00Phuc Phung-Vanpv.phuc86@hutech.edu.vnHung Tan Phamhungpht@hcmute.edu.vnHuy Nguyen-Giang.huy@hutech.edu.vnHung Nguyen-Xuanngx.hung@hutech.edu.vn<p><span lang="EN-US">This paper explores a free vibration analysis of functionally graded triply periodic minimal surface plates using a first order shear deformation theory in conjunction with moving Kriging meshfree method. </span>The FG-TPMS plates are modeled the same as porous structures with three different patterns (Primitive, Gyroid, and wrapped package-graph) and six different volume distributions for each pattern. Employing a fitting method based on a two-phase piece-wise function, the mechanical properties of the FGTPMS plates are determined. The governing equations for the FG-TPMS plates are established using the virtual work principle and subsequently solved using the moving Kriging meshfree method. The study encompasses FG-TPMS square and circular plate, examining the natural frequency of the FG-TPMS plates with various length-to-thickness ratios, TPMS types, volume distributions, and boundary conditions.</p>2023-12-30T20:04:18+07:00Copyright (c) 2023 Journal of Advanced Engineering and Computation